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Solutions of Certain Types of Linear and Nonlinear Diffusion-Reaction Equations in One Dimension
R. S. Kaushal
Physics , 2004,
Abstract: With a view to having further insight into the mathematical content of the non-Hermitian Hamiltonian associaterd with the diffusion-reaction (D-R) equation in one dimension, we investigate (a) the solitary wave solutions of certain types of its nonlinear versions, and (b) the problem of real eigenvalue spectrum associated with its linear version or with this class of non-Hermitian Hamiltonians. For the case (a) we use the standard techniques to handle the quadratic and cubic nonlinearities in the D-R equation whereas for the case (b) a newly proposed method, based on an extended complex phase space, is employed. For a particular class of solutions, an Ermakov system of equations is also found for the linear case. Further, corresponding to the 'classical' version of the above one-dimensional complex Hamiltonian, an equivalent integrable system of two, two-dimensional real Hamiltonians is suggested.
Delay Resistant Transport Protocol for Deep Space Communication  [PDF]
Mohanchur Sarkar, Kaushal K. Shukla, Kankar S. Dasgupta
Int'l J. of Communications, Network and System Sciences (IJCNS) , 2011, DOI: 10.4236/ijcns.2011.42015
Abstract: The throughput of conventional transport protocols suffers significant degradation with the increased Round Trip Time (RTT) typically seen in deep space communication. This paper proposes a Delay Resistant Transport Protocol (DR-TCP) for point-to-point communication in deep space exploration missions. The issues related to deep space communication protocol design and the areas where modifications are necessary are investigated, and a protocol is designed that can provide good throughput to the applications using a deep space link. The proposed protocol uses a cross layer based approach to find the allocated bandwidth and avoids initial bandwidth estimation. A novel timeout algorithm estimates the timeout duration with an objective to maximize throughput and avoid spurious timeout events. The protocol is evaluated through extensive simulations in ns2 considering high RTT values typically seen in Lunar and Mars Exploration Networks under different conditions of packet error rates. DR-TCP provides a significant increase in the throughput as compared to traditional transport protocols under the same conditions. A novel adaptive redundant retransmission algorithm is also presented to take care of the high PER in deep space links. The effect of the Retransmission Frequency has been critically analyzed considering both Lunar and Deep Space scenarios under different levels of PER. The results are very encouraging even in high error conditions. The protocol exhibits a RTT independent behavior in throughput, which is the most desirable quality of a protocol for deep space communication.
Warming increases carbon and nutrient fluxes from sediments in streams across land use
S.-W. Duan ,S. S. Kaushal
Biogeosciences (BG) & Discussions (BGD) , 2013,
Abstract: Rising water temperatures due to climate and land use change can accelerate biogeochemical fluxes from sediments to streams. We investigated impacts of increased streamwater temperatures on sediment fluxes of dissolved organic carbon (DOC), nitrate, soluble reactive phosphorus (SRP) and sulfate. Experiments were conducted at 8 long-term monitoring sites across land use (forest, agricultural, suburban, and urban) at the Baltimore Ecosystem Study Long-Term Ecological Research (LTER) site in the Chesapeake Bay watershed. Over 20 yr of routine water temperature data showed substantial variation across seasons and years. Lab incubations of sediment and overlying water were conducted at 4 temperatures (4 °C, 15 °C, 25 °C, and 35 °C) for 48 h. Results indicated: (1) warming significantly increased sediment DOC fluxes to overlying water across land use but decreased DOC quality via increases in the humic-like to protein-like fractions, (2) warming consistently increased SRP fluxes from sediments to overlying water across land use, (3) warming increased sulfate fluxes from sediments to overlying water at rural/suburban sites but decreased sulfate fluxes at some urban sites likely due to sulfate reduction, and (4) nitrate fluxes showed an increasing trend with temperature at some forest and urban sites but with larger variability than SRP. Sediment fluxes of nitrate, SRP and sulfate were strongly related to watershed urbanization and organic matter content. Using relationships of sediment fluxes with temperature, we estimate a 5 °C warming would increase mean sediment fluxes of SRP, DOC and nitrate-N across streams by 0.27–1.37 g m 2 yr 1, 0.03–0.14 kg m 2 yr 1, and 0.001–0.06 kg m 2 yr 1. Understanding warming impacts on coupled biogeochemical cycles in streams (e.g., organic matter mineralization, P sorption, nitrification, denitrification, and sulfate reduction) is critical for forecasting shifts in carbon and nutrient loads in response to interactive impacts of climate and land use change.
Warming increases carbon and nutrient fluxes from sediments in streams across land use
S.-W. Duan,S. S. Kaushal
Biogeosciences (BG) & Discussions (BGD) , 2013, DOI: 10.5194/bg-10-1193-2013
Abstract: Rising water temperatures due to climate and land use change can accelerate biogeochemical fluxes from sediments to streams. We investigated impacts of increased streamwater temperatures on sediment fluxes of dissolved organic carbon (DOC), nitrate, soluble reactive phosphorus (SRP) and sulfate. Experiments were conducted at 8 long-term monitoring sites across land use (forest, agricultural, suburban, and urban) at the Baltimore Ecosystem Study Long-Term Ecological Research (LTER) site in the Chesapeake Bay watershed. Over 20 yr of routine water temperature data showed substantial variation across seasons and years. Lab incubations of sediment and overlying water were conducted at 4 temperatures (4 °C, 15 °C, 25 °C, and 35 °C) for 48 h. Results indicated: (1) warming significantly increased sediment DOC fluxes to overlying water across land use but decreased DOC quality via increases in the humic-like to protein-like fractions, (2) warming consistently increased SRP fluxes from sediments to overlying water across land use, (3) warming increased sulfate fluxes from sediments to overlying water at rural/suburban sites but decreased sulfate fluxes at some urban sites likely due to sulfate reduction, and (4) nitrate fluxes showed an increasing trend with temperature at some forest and urban sites but with larger variability than SRP. Sediment fluxes of nitrate, SRP and sulfate were strongly related to watershed urbanization and organic matter content. Using relationships of sediment fluxes with temperature, we estimate a 5 °C warming would increase mean sediment fluxes of SRP, DOC and nitrate-N across streams by 0.27–1.37 g m 2 yr 1, 0.03–0.14 kg m 2 yr 1, and 0.001–0.06 kg m 2 yr 1. Understanding warming impacts on coupled biogeochemical cycles in streams (e.g., organic matter mineralization, P sorption, nitrification, denitrification, and sulfate reduction) is critical for forecasting shifts in carbon and nutrient loads in response to interactive impacts of climate and land use change.
Warming increases carbon-nutrient fluxes from sediments in streams across land use
S.-W. Duan,S. S. Kaushal
Biogeosciences Discussions , 2012, DOI: 10.5194/bgd-9-11293-2012
Abstract: Rising water temperatures due to climate and land-use change can accelerate biogeochemical fluxes from sediments to streams. We investigated impacts of increased streamwater temperatures on sediment fluxes of dissolved organic carbon (DOC), nitrate, soluble reactive phosphorus (SRP) and sulfate. Experiments were conducted at 8 long-term monitoring sites across land use (forest, agricultural, suburban, and urban) at the Baltimore Ecosystem Study Long-Term Ecological Research (LTER) site in the Chesapeake Bay watershed. Over 20 yr of routine water temperature data showed substantial variation across seasons and years, and lab incubations were conducted at 4 temperatures (4 °C, 15 °C, 25 °C and 35 °C) for 48 h. Results indicated: (1) warming consistently increased sediment DOC fluxes to overlying water across land use but decreased DOC quality via increases in the humic-like to protein-like fractions (2) warming consistently increased SRP fluxes from sediments to overlying water across land use (3) warming increased sulfate fluxes from sediments to overlying water at rural/suburban sites but decreased sulfate fluxes at urban sites likely due to sulfate reduction (4) nitrate fluxes showed an increasing trend with temperature but with larger variability than SRP. Sediment fluxes of nitrate, SRP and sulfate were strongly related to watershed urbanization and organic matter content. Using relationships of sediment fluxes with temperature, we estimate a 5 °C warming would increase the annual sediment release by 1.0–3.9 times. In addition to hydrologic variability, understanding warming impacts on coupled biogeochemical cycles in streams (e.g., organic matter mineralization, P sorption, nitrification, denitrification, and sulfate reduction) is critical for forecasting changes in carbon and nutrient exports across watershed land use.
Smoking cessation
Kaur K, Juneja S, Kaushal S
Clinical Pharmacology: Advances and Applications , 2012, DOI: http://dx.doi.org/10.2147/CPAA.S30323
Abstract: Smoking cessation Letter (2831) Total Article Views Authors: Kaur K, Juneja S, Kaushal S Published Date March 2012 Volume 2012:4 Pages 21 - 22 DOI: http://dx.doi.org/10.2147/CPAA.S30323 Received: 29 January 2012 Accepted: 02 February 2012 Published: 15 March 2012 Kirandeep Kaur, Shivani Juneja, Sandeep Kaushal Department of Pharmacology, Dayanand Medical College and Hospital, Ludhiana, Punjab, India With reference to the article published under the title "Pharmacologic agents for smoking cessation: A clinical review", we would like to add some information related to smoking cessation therapy among pregnant females. In that article, in the nicotine replacement therapy section, pregnancy has been considered as a contraindication to the use of transdermal patches, gum, lozenges, nasal sprays, and oral inhalers containing nicotine. Post to: Cannotea Citeulike Del.icio.us Facebook LinkedIn Twitter Readers of this article also read: The cognitive impact of anticholinergics: A clinical review Polyphenols as dietary supplements: A double-edged sword Pharmacologic agents for smoking cessation: A clinical review Cumulative clinical experience from over a decade of use of levofloxacin in community-acquired pneumonia: critical appraisal and role in therapy Iris and periocular adverse reactions to bimatoprost in Japanese patients with glaucoma or ocular hypertension Nortriptyline versus fluoxetine in the treatment of major depressive disorder: a six-month, double-blind clinical trial Phase 1 clinical study of the acute and subacute safety and proof-of-concept efficacy of carbohydrate-derived fulvic acid Influence of paraoxonase-1 Q192R and cytochrome P450 2C19 polymorphisms on clopidogrel response Management of antipsychotic treatment discontinuation and interruptions using model-based simulations Loading regimen required to rapidly achieve therapeutic trough plasma concentration of teicoplanin and evaluation of clinical features
Smoking cessation
Kaur K,Juneja S,Kaushal S
Clinical Pharmacology: Advances and Applications , 2012,
Abstract: Kirandeep Kaur, Shivani Juneja, Sandeep KaushalDepartment of Pharmacology, Dayanand Medical College and Hospital, Ludhiana, Punjab, IndiaWith reference to the article published under the title "Pharmacologic agents for smoking cessation: A clinical review", we would like to add some information related to smoking cessation therapy among pregnant females. In that article, in the nicotine replacement therapy section, pregnancy has been considered as a contraindication to the use of transdermal patches, gum, lozenges, nasal sprays, and oral inhalers containing nicotine.
Effect of different non-steroidal anti-inflammatory drugs, aspirin, nimesulide and celecoxib on the disaccharide hydrolases and histoarchitecture of the rat intestinal brush border membrane
Sood,N.; Kaushal,N.; Sanyal,S. N.;
Nutrición Hospitalaria , 2008,
Abstract: non-steroidal anti-inflammatory drugs (nsaids) are known to cause gastrointestinal damage. new anti-inflammatory drugs have been developed in an attemptto improve their gastrointestinal side effect profile which however failed to do so. therefore, the objective of the present study was to compare the effect of three different nsaids, aspirin, nimesulide and celecoxib on the intestinal brush border membrane (bbm) marker enzymes and correlate these alterations to the histoarchtecture of the intestine using electron microscopic study. female wistar rats were divided into four different groups viz: group i (control), group ii (aspirin treated), group iii (nimesulide treated) and group iv (celecoxib treated). the group ii, iii and iv received the corresponding drugs dissolved in water orally at a dose of 40 mg/kg body weight, while the control received the vehicle only. after 28 days, all the treatment groups demonstrated significant alterations in the activities of intestinal disaccharide hydrolases and alkaline phosphatase in both the crude homogenates and bbm preparations as well. the histopathological observations also showed considerable changes in the intestinal mucosa. it was suggested that nsaids like aspirin, nimesulide and celecoxib pose intestinal side effects due to initial changes in the enzymatic composition of the intestinal apical membranes. it was further concluded that newly discovered nsaids such as celecoxib has better safety profiles but studies are still required to comment decisively on the suitability of various nsaids depending upon their cyclooxygenase enzyme specificity.
Comments on the article ′Antimicrobial and analgesic activities of Wendlandia thyrsoidea leaf extracts′
Gupta Kanchan,Chopra S,Kaushal Sandeep
International Journal of Green Pharmacy , 2010,
Abstract:
Failure of titer of contact hypersensitivity to correlate with clinical severity and therapeutic response in contact dermatitis caused by parthenium
Verma Kaushal,Manchanda Yashpal,Dwivedi S
Indian Journal of Dermatology, Venereology and Leprology , 2004,
Abstract: Background: The titer of contact hypersensitivity (TCH) has been used to determine the degree of contact hypersensitivity in patients with contact dermatitis. The values have been found to vary in different individuals and also in the same individual at different times apparently due to the varying severity of the disease. We evaluated the correlation of TCH with disease severity and therapeutic response in patients of contact dermatitis caused by the plant Parthenium hysterophorus. Methods: Forty-two patients, 30 (71.4%) males and 12 (28.6%) females, aged between 30-75 years, having air-borne contact dermatitis to Parthenium hysterophorus for 0.5-20 years were included in the study. The disease severity and TCH at baseline were recorded in all the patients. They were treated with azathioprine and followed up every month for 4-69 months. The TCH was repeated every 3 months and the last recorded TCH value was taken for analysis in each patient. Results: The baseline clinical severity score (CSS) varied from 10-80 (mean ± SD: 35.47 ± 19.41) in these patients. It ranged from 10-30 in 22 (52.4%) patients, from 31-50 in 14 (33.3%) patients, and was more than 50 in 6 (14.3%) patients. The baseline TCH to Parthenium was undiluted (UD) in 2 (4.8%), 1:10 in 15 (35.7%), 1:100 in 20 (47.6%), and 1:1000 in 5 (11.9%) patients respectively. At the end of the study, the clinical severity of the disease decreased in most of the patients. The CSS came down to 0 in 31 patients, to 10-20, and to 50 in 4 patients each, but remained stable in three patients who had baseline CSS from 20-40. The overall mean CSS came down from 35.47 ± 19.41 to 4.76 ± 9.43 (p = 0.002). However, there was no significant change in the TCH levels over time (p = 0.153). The last TCH value was negative in 2 (4.8%) patients, undiluted in 5 (11.9%), 1:10 in 10 (23.8%), 1:100 in 18 (42.9%), and 1:1000 in 7 (16.7%) patients. There was no change in the TCH values in 16 (38.1%) patients while it increased or decreased by 1-2 dilutions in 12 (28.6%) patients each. Conclusions: We therefore conclude that the TCH does not correlate with the clinical severity of contact dermatitis or response to treatment.
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